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Doxycycline: This prevents the malaria parasite from reproducing and kills in the process. Protection only starts 1-2 days after taking medication, hence the need to start treatment before travelling to ensure you are protected on arrival at your destination. Doxycycline provides 90-100% protection when used in conjunction with other measures.
Lariam® (Mefloquine 250mg): Lariam interferes with the growth of the malaria parasites in the red blood cells. For it to be effective at the destination, you must start taking it at least 10 days before you depart. Usually the 2nd dose is taken 7 days after the first and 3 days before departure. It is best taken with food and adequate water (on the same day each week) in order to prevent any stomach upset. As with other antimalarials, protection isn't guaranteed and other bite prevention measures must be taken alongside it. It is suitable for both adults and young children.
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